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The endocrine system is the collection of glands in the body that secrete hormones into the bloodstream to be carried towards distant target organs. The central neuroendocrine systems is the interface between the brain and the rest of the endocrine systems. The part of the brain that balances the release of hormones in the body is called the hypothalamus and sits right on top of the pituitary gland where it regulates stress, metabolism, growth, reproduction, and lactation. All of these processes are regulated by the hypothalamus releasing or inhibiting the release of hormones by the pituitary gland. The release of pituitary hormones affects downstream physiological functions. Other hypothalamic neuroendocrine cells control water/salt balance, and lactation and childbirth, through the release of vasopressin and oxytocin. Together, these hypothalamic neuroendocrine functions enable the central nervous system to respond rapidly to internal or external environmental change, and to maintain a response through endocrine hormonal transducers. The endocannabinoid system modulates the regulation of the neuroendocrine system, which regulates organ function and stress response and helps maintain a healthy balance across the neuroendocrine system and related physiological body system.
This brings us to the cannabinoid du jour, cannabidiol or CBD. Long playing the second fiddle to the more active tetrahydrocannabinol (THC). CBD does not interact strongly with either the CB1 or CB2 receptors. Instead, it is able to increase endocannabinoid tone by inhibiting fatty acid amide hydrolase (FAAH), and enzyme that breaks down cannabinoids in the body. FAAH inhibitors may be may be helpful for people with anxiety-related disorders because they appear to improve the regulation of the HPA axis. It’s unknown precisely how this happens, how this happens but it appears they help to modulate the sensitivity of the cannabinoid receptors in the body.in the body.
In addition to its stimulatory effects on HPA, the ECS also plays a critical inhibitory role in regulating HPA functions. Researchers found that endocannabinoid signaling negatively modulates the stress-induced activation of the HPA axis, confirming the notion that an increase in endocannabinoid signaling activity may constitute a novel approach to improving the lives of people with anxiety-related disorders.
Currently, the best way to boost endocannabinoid signaling, improve the regulation of the HPA, and promote a healthy endocrine system is the use of a dietary cannabinoid supplement made from hemp..
CBD has been shown to lower anxiety, stress, level blood sugars, reduce depression, help with chronic pain & inflammation. People with PTSD, Autism and seizures have greatly benefited. CBD also helps with insomnia and our THC -free products will NOT show up in a drug test!
CBD used as a topical can help with the healing of bruises, scrapes, eczema, psoriasis, arthritis, joint pain, rashes and dermatitis and more! Our
CBD is non-psychoative and will NOT get you high!
Our healing salve comes in two convenient sizes and has been shown to heal eczema, psorisis, sore muscles and arthritic joints. It heals scrapes, bruises and burns in record time. Our salves are made with all organic, non gmo products and we are extremely proud of them! Our 2 oz can has packed with 1000 mg of CBD and is our best value and our 1 oz has 500 mg of CBD. Both work wonders! Please check out our amazing 5 star reviews!
We offer 500 & 1000 mg tinctures (CBD oil)
Using the finest organic coconut based MCT on the market. We also have a sunburn relief spray that works wonders on sunburns! Some of our products are THC free, so you never have to worry about passing drug tests! We now offer full spectrum CBD tinctures and vapes. Always organic and hand crafted with love. Small batch artisan quality!
We are happy to offer packages shipped directly to your home or work place and we will gladly customize for gift giving :) $5 extra per order.
Gift giving packaged with love & aloha! Your loved one will feel the love and healing spirit of Hawaii!
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Our CBD company started In 2018 after much research and finding the perfect ingredients for our small batch salves, muscle rubs and tinctures. We strive to only use organic, paraban free, non-gmo and pesticide free ingredients. We take great pride in our products and have compelling testimony from Hawaii and as far as Switzerland! We value our customers and can also do special orders for people who may be allergic to certain ingredients. Please like our Facebook and Instagram page where we regularly offer ''friends & family'' discounts!
All of our CBD is grown in Colorado & Northern California. We have 3rd party lab testing and paperwork that shows our outstanding reports! Feel free to ask us and we will happily provide you the batch number and lab results! .
Please feel free to contact a member of our staff directly with any questions, comments, or inquiries you may have. We ship
and have several methods payment for your convenience. Call us at 808-664-4248 or email us at firstname.lastname@example.org
We treat you like ohana and would love to hear from you!
PO Box 672 Pahoa, HI 96778
Monday - Friday: 8 am - 6 pm
Saturday: Consultations by appointment